Thesis work, 30/60 credits - Cryopreservation and Characterization of iPSC-Derived Organoids

Are you interested in stem cell biology and advanced cell models, and wish to contribute to cutting-edge research in pharmaceutical science? Do you want hands-on experience in organoid technology, cell banking, and multi-omics analysis? Join AstraZeneca’s collaborative effort between the Global Cell Bank (GCB) and the Safety Omics team and help us advance the future of drug development! 

About AstraZeneca: 

AstraZeneca is a global, science-led, patient-centered biopharmaceutical company focusing on discovering, developing, and commercializing prescription medicines for some of the world’s most serious diseases. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.  

About the Opportunity: 

As a Thesis Worker at AstraZeneca, you’ll find an environment that’s full of unique opportunities and exciting challenges. Here, you’ll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. You’ll be working on meaningful projects to make an impact and deliver real value for our patients and our business. 

Thesis work description 
In this master’s thesis, you will work to optimize the cryopreservation of organoids generated from induced pluripotent stem cells (iPSCs). You will be responsible for refining freezing and storage protocols to ensure organoid viability and quality upon recovery. In addition, you will perform a broad range of assays to characterize these organoids—assessing their viability, functionality, molecular and structural identity, and performing comparisons based on multi-omics data. 

This opportunity involves close interaction with expert teams in cell banking and omics technologies. If you have a background in cell biology, biotechnology, molecular biology, or related fields—and an interest in the latest methods in cell culture and bioanalytics—this project will give you valuable skills and experience on the frontier of pharmaceutical research. 

Structure: 

• Duration: Spring term 2026 
• Credits: 30/60 

Requirements: 

• Ongoing master’s studies within the life science field 
• Scientific curiosity in cell culture sciences 
• Experience with culturing cells (advanced cell types, 3D models is a plus) 
• Experience with imaging, immunofluorescence studies 
• Molecular biology techniques such as RNA isolation, qPCR 
• Analytical thinking, prior laboratory research experience 

So, what’s next?  

Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can't wait to hear from you!  

We welcome your application as soon as possible, but ahead of the scheduled closing date 31st of October 2025. In the event that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.  

Date Posted

16-okt.-2025

Closing Date

31-okt.-2025

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.